Activated protein C inhibit clotting mechanism by inactivating which of the following clotting factors:
Correct Answer: Factor Va and Factor VIIIa
Description: Protein-C is a vitamin K-dependent protease that requires a cofactor (Protein S). Activated Protein C/protein S forms a complex which is a potent inhibitor of coagulation factors Va and Factor VIIIa. Protein C acts as a Tissue factor pathway inhibitor (TFPI)
Category:
Pathology
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