**Core Concept**
Bacterial adhesion to tooth surfaces is a critical step in the development of dental plaque and periodontal disease. Actinobacillus actinomycetemcomitans (Aa) is a periodontal pathogen that adheres to tooth surfaces, contributing to the progression of periodontitis.

**Why the Correct Answer is Right**
The correct answer involves the use of chlorhexidine, a disinfectant and antiseptic that prevents bacterial adhesion to tooth surfaces. Chlorhexidine works by disrupting the formation of biofilms, which are complex communities of microorganisms that adhere to surfaces and are resistant to antimicrobial agents. Chlorhexidine binds to negatively charged bacterial cell surfaces, inhibiting the formation of biofilms and preventing the adhesion of periodontal pathogens like Actinobacillus actinomycetemcomitans.

**Why Each Wrong Option is Incorrect**
**Option A:** **None of the above** - This option is incorrect because there are indeed specific agents that can prevent bacterial adhesion to tooth surfaces.
**Option B:** **Tetracycline** - This option is incorrect because while tetracycline has antimicrobial properties, it does not specifically prevent bacterial adhesion to tooth surfaces.
**Option C:** **Fluoride** - This option is incorrect because while fluoride has antibacterial properties and is used in oral care products, it does not specifically prevent bacterial adhesion to tooth surfaces.

**Clinical Pearl / High-Yield Fact**
Chlorhexidine is a potent antiseptic that can be used to prevent bacterial adhesion to tooth surfaces, making it a useful adjunct in the prevention and treatment of periodontal disease.

**Correct Answer: D. Chlorhexidine**