**Core Concept**
Acrodermatitis enteropathica is a rare genetic disorder characterized by impaired zinc absorption, leading to severe zinc deficiency. It is caused by mutations in the SLC39A4 gene, which encodes a zinc transporter responsible for zinc uptake in the intestine.

**Why the Correct Answer is Right**
The correct answer is A. Lifelong treatment required. Patients with acrodermatitis enteropathica require lifelong zinc supplementation to manage their condition. This is because the underlying genetic defect affects zinc absorption, making it impossible for the body to obtain sufficient zinc from the diet. Zinc is essential for various cellular functions, including protein synthesis, DNA replication, and immune function. Without adequate zinc, patients may experience a range of symptoms, including skin lesions, hair loss, and impaired wound healing.

**Why Each Wrong Option is Incorrect**
**Option B:** Autosomal dominant disorder. Acrodermatitis enteropathica is actually an autosomal recessive disorder, meaning that patients must inherit two copies of the mutated gene (one from each parent) to develop the condition.

**Option C:** Wound healing is not affected. In fact, impaired zinc levels can significantly impede wound healing, as zinc plays a crucial role in tissue repair and collagen synthesis.

**Option D:** Zinc absorption is normal. As mentioned earlier, acrodermatitis enteropathica is characterized by impaired zinc absorption, making this statement incorrect.

**Clinical Pearl / High-Yield Fact**
It's essential to note that patients with acrodermatitis enteropathica may require high doses of zinc supplementation to manage their condition, and monitoring of zinc levels is crucial to prevent toxicity.

**Correct Answer:**
✓ Correct Answer: A. Lifelong treatment required