Acetyl CoA is formed from glucose. Following are the fate of Acetyl CoA after its formation: Oxidation in TCA cycle to form CO2 AND H2O Cholesterol biosynthesis Ketogenesis Fatty acid synthesis Acetylation reactions (Detoxication) Formation of acetyl choline Melatonin synthesis Ref: Textbook of Medical Biochemistry By Chatterjea, 2011, Page 442.