Medical MCQ-Acetazolamide is given to a patient of angle closure glaucoma. It is a non-competitive inhibitor of carbonic anhydrase enzyme. Which of the following should be the effect of this drug?

Acetazolamide is given to a patient of angle closure glaucoma. It is a non-competitive inhibitor of carbonic anhydrase enzyme. Which of the following should be the effect of this drug?

Decrease in Vmax

A.Decrease in Km

Increase in both Km and Vmax

No change in Vmax

Question Category:

Pharmacology

Correct Answer:

Decrease in Vmax

Description:

* Enzyme inhibition is of 3 types: Type of inhibition Km Vmax Competitive inhibition Increases No change Non competitive inhibition No change Decreases Uncompetitive inhibition Decreases Decreases * In question non competitive inhibitor is given, so answer is decrease in Vmax.

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