According to WHO all are B cell lymphomas except?
**Core Concept**
WHO classification of lymphomas is a widely accepted system for categorizing lymphoid malignancies. It distinguishes between B cell and T cell lymphomas based on their immunophenotypic and genetic characteristics.
**Why the Correct Answer is Right**
The WHO classification of lymphomas includes several B cell lymphomas, such as Diffuse Large B cell Lymphoma (DLBCL), Follicular Lymphoma, and Mantle Cell Lymphoma, among others. These B cell lymphomas arise from the malignant transformation of mature B cells. In contrast, the correct answer is a type of lymphoma that does not originate from B cells.
**Why Each Wrong Option is Incorrect**
* **Option A:** This option is incorrect because it is a type of B cell lymphoma, specifically a subtype of mature B cell neoplasm. It arises from the malignant transformation of germinal center B cells.
* **Option B:** This option is incorrect because it is a type of B cell lymphoma, characterized by its distinctive morphology and immunophenotype. It is a subtype of mature B cell neoplasm.
* **Option C:** This option is incorrect because it is a type of B cell lymphoma, arising from the malignant transformation of post-germinal center B cells. It is a subtype of mature B cell neoplasm.
**Clinical Pearl / High-Yield Fact**
The WHO classification of lymphomas is essential for accurate diagnosis and treatment planning. Familiarity with the different subtypes of B cell and T cell lymphomas can help clinicians make informed decisions about patient care.
**Correct Answer:** D.