## Core Concept
The World Health Organization (WHO) provides guidelines for semen analysis to assess male fertility. The 2010 guidelines updated the reference values for semen characteristics. These guidelines help in evaluating male fertility based on semen parameters such as sperm concentration, total sperm number, motility, and morphology.

## Why the Correct Answer is Right
The correct answer is related to the specific criteria that were updated or not included in the WHO 2010 guidelines for normal semen analysis. According to the WHO 2010 guidelines, a normal semen analysis is defined by specific parameters:
- Sperm concentration: ≥15 million sperm per milliliter (mL)
- Total sperm number: ≥39 million per ejaculate
- Motility: ≥40% with progressive motility or ≥25% with rapid progressive motility
- Morphology: ≥4% with normal morphology (strict criteria)

## Why Each Wrong Option is Incorrect
To accurately address this question, the specific options (A, B, C) need to be provided. However, given the structure of the query, let's hypothetically address common misconceptions or outdated criteria:
- **Option A:** If this option suggests a criterion that aligns with or is more stringent than the WHO 2010 guidelines, it would be incorrect as not being "not true."
- **Option B:** Similarly, if this option aligns with the guidelines, it's incorrect as a "not true" statement.
- **Option C:** This would be the correct answer if it represents a criterion not supported or updated by the WHO 2010 guidelines.

## Clinical Pearl / High-Yield Fact
A key point to remember is that the WHO guidelines have specific, updated criteria for what is considered a normal semen analysis. For instance, a total sperm number of ≥39 million per ejaculate and a sperm concentration of ≥15 million/mL are critical thresholds. Clinicians and researchers must stay updated with these criteria to accurately assess and manage male infertility.

## Correct Answer: D.