Acclimatization does not include:
Correct Answer: Decreased concentration of 2,3 DPG in RBC
Description: Acclimatization: The respiratory alkalosis produced by the hyperventilation shifts the oxygen-hemoglobin dissociation curve to the left, but a concomitant increase in red blood cell 2,3-BPG tends to decrease the O2 affinity of hemoglobin. The net effect is a small increase in P50 (right shift).
Erythropoietin secretion increases promptly on ascent to high altitude. The increase in circulating red blood cells triggered by the erythropoietin begins in 2-3 days and is sustained as long as the individual remains at high altitude.
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