**Core Concept**
Systemic absorption of lidocaine, a local anesthetic and antiarrhythmic medication, can lead to various systemic side effects due to its effects on the central nervous system and cardiovascular system.

**Why the Correct Answer is Right**
Lidocaine's systemic absorption can cause central nervous system (CNS) effects such as dizziness, confusion, and seizures. Additionally, it can cause cardiovascular effects such as hypotension, bradycardia, and arrhythmias. The correct answer is one that does not align with these known side effects.

**Why Each Wrong Option is Incorrect**
**Option A:** CNS effects such as dizziness and confusion are well-documented side effects of systemic lidocaine absorption.
**Option C:** Arrhythmias are a potential side effect of systemic lidocaine absorption, particularly in high doses.
**Option D:** Hypotension is a possible side effect of systemic lidocaine absorption due to its vasodilatory effects.

**Clinical Pearl / High-Yield Fact**
It is essential to monitor patients closely for signs of systemic lidocaine absorption, particularly when using large doses or when administering lidocaine via a peripheral nerve block.

**Correct Answer: B.**