Absolutely contraindicated antihypeensive drug in pregnancy is-
**Core Concept**
The question is testing knowledge of antihypertensive medications that are contraindicated in pregnancy. In pregnancy, certain antihypertensive medications can cause fetal harm or have adverse effects on maternal and fetal health.
**Why the Correct Answer is Right**
The correct answer is Labetalol. Labetalol is a mixed alpha and beta-blocker that is often used in pregnancy-induced hypertension. It is considered safe for use in pregnancy due to its favorable pharmacokinetic profile and lower risk of fetal harm. However, other antihypertensive medications like Minoxidil and Hydralazine are often avoided in pregnancy due to their potential for causing fetal harm.
**Why Each Wrong Option is Incorrect**
**Option A:** Minoxidil is a potent vasodilator that is contraindicated in pregnancy due to its potential to cause fetal hypoxia and cardiac effects.
**Option B:** Hydralazine is a vasodilator that is often used in pregnancy-induced hypertension, but it can cause maternal and fetal tachycardia and is not absolutely contraindicated.
**Option C:** Methyldopa is an antihypertensive medication that is often used in pregnancy and is considered safe for use in pregnancy.
**Clinical Pearl / High-Yield Fact**
Always remember that the choice of antihypertensive medication in pregnancy depends on the severity of hypertension, gestational age, and maternal and fetal health status.
**Correct Answer:** C. Methyldopa.