About Ramelton false is –
Correct Answer: Has high addictive potential
Description: Ans. is 'c' i.e., Has high addictive potential Ramelteon is the most recently FDA approved hypnotic. It is a novel agent (novel hypnotic) with high selectivity for the melatonin receptors MTI and MT2. The CYP1A2 isoform of cytochrome P450 is mainly responsible for the metabolism of ramelteon and should not be used with fluvoxamine (an inhibitor of CYP1 A2). Ramelteon is used in the treatment of insomnia when the patient has difficulty in falling asleep. Ramelteon has not been found to cause rebound insomnia or withdrawal symptoms, unlike benzodiazepines; neither does it seem to pose a risk for abuse or tolerance. Thus, unlike other hypnotics, ramelteon is not a controlled substance.
Category:
Pharmacology
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