About peptidyl transferase true is:
Correct Answer: Used in elongation and cause attachment of peptide chain to A-site of tRNA
Description: Ans. A. Used in elongation and cause attachment of peptide chain to A-site of tRNA(Ref: Harper 31/e page 403)The a amino group of the new aminoacyl-tRNA in the A site carries out a nucleophilic attack on the esterified carboxyl group of the peptidyl-tRNA occupying the P site (peptidyl or polypeptide site). At initiation, this site is occupied by the initiator met-tRNAi.This reaction is catalyzed by a peptidyl transferase, a component of the 28S RNA of the 60S ribosomal subunit.This is another example of ribozyme activity.
Category:
Biochemistry
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