About Langerhans cell histiocytosis, true are all except:
Correct Answer: Gonadal involvement occurs
Description: d. Gonadal involvement occurs(Ref: Nelson's 20/e p 2484-2489; Ghai 8/e p 620-623)a. Peak incidence less than 3 years of age: True; More common and more severe in younger childrenb. Radiosensitive: True, as Bone lesions and Pituitary lesions, causing DI, respond well to radiotherapyc. Diffuse form is known as Letterer-Siwe disease: Trued. Gonadal involvement occurs: FALSE; Gonadal involvement is usually not seen in LCH.
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