**Question:** About Fibronectin nephropathy, which of the following is false?

A. Fibronectin nephropathy is a rare disorder
B. Fibronectin is a protein involved in wound healing and immune response
C. Fibronectin plays a role in maintaining the integrity of the glomerular basement membrane
D. Fibronectin nephropathy is a common cause of kidney failure

**Core Concept:**
Fibronectin is a glycoprotein that plays a crucial role in wound healing, immune response, and maintaining the integrity of the glomerular basement membrane in the kidneys. It is essential for proper functioning of the kidneys.

**Why the Correct Answer is Right:**
Fibronectin nephropathy is a rare disorder, which means it is not a common cause of kidney failure. While fibronectin does play an important role in wound healing and immune response, and is vital for maintaining the integrity of the glomerular basement membrane, it is not the primary cause of kidney failure.

**Why Each Wrong Option is Incorrect:**
A. Fibronectin nephropathy is a rare disorder - This statement is true, making option A incorrect.
B. Fibronectin is not the primary cause of kidney failure - While it is involved in wound healing and immune response, it is not the main cause of kidney failure, making option B incorrect.
C. Fibronectin plays a role in maintaining the integrity of the glomerular basement membrane - This statement is true, making option C incorrect.
D. Fibronectin nephropathy is a common cause of kidney failure - This statement is false, making option D incorrect.

**Clinical Pearl:**
Fibronectin nephropathy is an uncommon disease characterized by abnormal fibronectin deposition in the kidneys, leading to kidney dysfunction. Understanding the role of fibronectin in wound healing, immune response, and glomerular basement membrane maintenance is important for recognizing this rare condition in clinical practice.