A study of colonic polyps is performed. Malignant cells localized to the polyp are compared to those from polyps showing invasion of the stalk. Molecular analysis shows up-regulation of certain molecules in the invasive malignant cells. Invasive lesions are more likely to exhibit lymphatic metastases. Which of the following markers is most likely to have increased expression in the invasive malignant epithelial cells?
A study of colonic polyps is performed. Malignant cells localized to the polyp are compared to those from polyps showing invasion of the stalk. Molecular analysis shows up-regulation of certain molecules in the invasive malignant cells. Invasive lesions are more likely to exhibit lymphatic metastases. Which of the following markers is most likely to have increased expression in the invasive malignant epithelial cells?
π‘ Explanation
A study of colonic polyps is performed. Malignant cells localized to the polyp are compared to those from polyps showing invasion of the stalk. Molecular analysis shows up-regulation of certain molecules in the invasive malignant cells. Invasive lesions are more likely to exhibit lymphatic metastases. Which of the following markers is most likely to have increased expression in the invasive malignant epithelial cells?
β Correct Answer: B. CD44
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