A primigravida in 2nd trimester became positive for toxoplasmosis. Veical transmission of toxoplasmosis MOST commonly occurs in which trimester?
Correct Answer: 3rd trimester
Description: In pregnancy, if the mother becomes infected during the first trimester, the incidence of transplacental infection is lowest (15%), but the disease in the neonate is most severe. If maternal infection occurs during the third trimester, the incidence of transplacental infection is greatest (65%), but the infant is usually asymptomatic at bih. Infected infants who are normal at bih may have a higher incidence of learning disabilities and chronic neurologic sequelae than uninfected children. Ref: Kim K., Kasper L.H. (2012). Chapter 214. Toxoplasma Infections. In D.L. Longo, A.S. Fauci, D.L. Kasper, S.L. Hauser, J.L. Jameson, J. Loscalzo (Eds),Harrison's Principles of Internal Medicine, 18e.
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Gynaecology & Obstetrics
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