A pregnant with known cardiac disease on warfarin for anticoagulation, presents soon after conception. What should be advised now?
Correct Answer: Replace warfarin with Unfractionated/LMW heparin in first trimester
Description: Warfarin is teratogenic and can cause miscarriage, stillbihs, and fetal malformation, therefore to be avoided in first trimester For first trimester (for period of organogenesis)- give LMWH or unfractioned Heparin From 13 weeks till early term(36 weeks), put patient on warfarin after 36 weeks, we again put the patient on LMWH or unfractioned heparin. This is because since the patient can now go into labour and since warfarin (longer half life than LMWH) takes a longer time for its anticoagulant action to reverse, it may lead to bleeding complications during delivery or LSCS.
Category:
Gynaecology & Obstetrics
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now