A pharmacologist is determining the pharmacokinetic parameters of a novel antibiotic in order to determine the proper dosage. The drug is a weak organic acid with a pKa of 3.0. Assuming a pH of 2.0 in the stomach, approximately what percent of the drug will be in a form that can be rapidly absorbed from the stomach?
A pharmacologist is determining the pharmacokinetic parameters of a novel antibiotic in order to determine the proper dosage. The drug is a weak organic acid with a pKa of 3.0. Assuming a pH of 2.0 in the stomach, approximately what percent of the drug will be in a form that can be rapidly absorbed from the stomach?
π‘ Explanation
A pharmacologist is determining the pharmacokinetic parameters of a novel antibiotic in order to determine the proper dosage. The drug is a weak organic acid with a pKa of 3.0. Assuming a pH of 2.0 in the stomach, approximately what percent of the drug will be in a form that can be rapidly absorbed from the stomach?
β Correct Answer: D. 90
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