A person is being treated for Human Immunodeficiency Virus-1. He developed hyperiglyceridemia and hypercholesterolemia. Most likely drug implicated for these adverse effects is:
Correct Answer: Ritonavir
Description: ANTIVIRAL DRUGS: Protease inhibitors: Ritonavir, Indinavir, Nelfinavir, Saquinavir, Amprenavir*, Lopinavir The most prominent adverse effects of protease inhibitors are gastrointestinal intolerance, asthenia, headache, dizziness, limb and facial tingling, numbness and rashes. Of paicular concern are lipodystrophy (abdominal obesity, buffalo hump with wasting of limbs and face) and dyslipidaemia (raised triglycerides and cholesterol) which may necessitate hypolipidaemic drugs. Diabetes may be exacerbated. Indinavir crystalises in urine and increases risk of urinary calculi. ESSENTIALS OF MEDICAL PHARMACOLOGY K.D.TRIPATHI SIXTH EDITION PAGE NO:773
Category:
Pharmacology
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now