Medical MCQ-A patient was taking warfarin and INR comes out to be 8. Next step would be to stop the drug and:-

A patient was taking warfarin and INR comes out to be 8. Next step would be to stop the drug and:-

Resta at a lower dose once the INR is in therapeutic range

Give oral vitamin K1

Administer fresh frozen plasma

Transfuse fresh blood

Question Category:

Pharmacology

Correct Answer:

Give oral vitamin K1

Description:

Management of warfarin overdose is done as follows: *INR < 5 but above therapeutic range - Discontinue warfarin temporarily and resta at low dose. *INR 5-9 - Vitamin K1 (1 mg oral) *INR > 9 but no bleeding - Vitamin K1 (2 - 3 mg oral) *INR > 20 or bleeding - Four factor prothrombin complex or Fresh frozen plasma.

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