Medical MCQ-A patient presents to emergency with pinpoint pupil, salivation, lacrimation, tremors and red tears. Plasma cholinesterase level was 30% of normal. Most probable Diagnosis is:

A patient presents to emergency with pinpoint pupil, salivation, lacrimation, tremors and red tears. Plasma cholinesterase level was 30% of normal. Most probable Diagnosis is:

Organophosphate poisoning

Datura poisoning

Opioid poisoning

Pontine hemorrhage

Question Category:

Pharmacology

Correct Answer:

Organophosphate poisoning

Description:

Ans. (A) Organophosphate poisoning(Ref: Katzung 12/e p110)These are characteristic features of anti-cholinestearse (organophosphate and carbamate) poisoning.Features of Organophosphate poisoning:* Muscarinic symptoms: Pin point pupil, salivation, lacrimation, urination, defecation, gastrointestinal distress, vomiting, bronchospasm, bradycardia* Nicotinic symptoms: Fasciculations and fibrillations of muscle, tachycardia, tachypnea* CNS symptoms: Temors, giddiness, ataxia, coma* Red tears: Due to accumulation of porphyrin in the lacrimal glands

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