A Patient on alcohol dependence was given a drug and was advised to avoid alcohol as drug interaction would lead to adverse drug reaction. Which of the following is the drug

Correct Answer: Disulfiram
Description: When alcohol is ingested by a person who is on disulfiram, alcohol-derived acetal de hyde cannot be oxidised to acetate and this leads to an accumulation of acetaldehyde in blood. This causes the impoant disulfiram-ethanol reaction (DER) characterised by flushing, tachycardia, hypotension, tachypnoea, palpitations, headache, sweating, nausea, vomiting, giddiness and a sense of impending doom associated with severe anxiety. Ref: A Sho Textbook of Psychiatry, Niraj Ahuja, 7th Edition, pg. no.41
Category: Psychiatry
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