Neurofibromatosis Type 2 Autosomal dominant disorder resulting in a range of tumors, most commonly bilateral eighth nerve schwannomas, multiple meningiomas, and ependymomas of the spinal cord. In addition, a characteristic type of cataract, juvenile posterior subcapsular lenticular opacity, occurs in NF2. This syndrome is caused by mutation of the NF2 gene on chromosome 22q; NF2 encodes a protein called neurofibromin 2/merlin protein.