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A neonate is being investigated for jaundice. A liver biopsy shows features of a “Giant Cell/Neonatal hepatitis”. Which one of the following conditions usually results in this case –

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Correct Answer:
Alpha–1–antitrypsin deficiency
Description:
Other conditions which also presents with similar clinical and histological features (i.e., with giant cells) a)   ai antitrypsin deficiency b) Alagille syndrome                   c) Niemann - Pick type C disease (NPC). d)   Viral infections                         e) Byler disease                    f) Progressive familial intrahepatic cholestasis (PFIC).
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