Medical MCQ-A neonate following BCG vaccination developed a side effect. Which of the following side effect would the neonate most likely develop after vaccination?

A neonate following BCG vaccination developed a side effect. Which of the following side effect would the neonate most likely develop after vaccination?

Fever

Ulceration

Osteomyelitis

Regional lymphadenitis

Question Category:

Microbiology

Correct Answer:

Ulceration

Description:

Ulceration is the most common side effect post BCG vaccination. Following vaccination, the local tissue response begins in 2-3 weeks, with scar formation and healing within 3 months. Side effects most commonly are ulceration at the vaccination site and regional lymphadenitis. Some vaccine strains also rarely cause osteomyelitis. In immunocompromised states, disseminated BCG infection can occur. Reference: Ananthanarayan and Paniker&;s Textbook of Microbiology Tenth edition

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