A middle aged female patient comes with recurrent painful blisters over oral mucosa and genital area. She gives history of similar lesion in the past. A biopsy from the lesion shows suprabasal split on histopathology and IgG deposits in immunofluorescence microscopy as shown below. What is the most likely diagnosis?
Correct Answer: Pemphigus vulgaris
Description: Clinical history like flaccid bullae, oral mucosal involvement, tendency to rupture and erode, is suggestive of pemphigus vulgaris. The Immunofluorescent examination finding in Pemphigus vulgaris are deposition of lgG3 & C3 in intercellular space giving fish net pattern.
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