Gynaecology & Obstetrics A major causal factor in some cases of hypogonadism is A Reduced secretion of gonadotropin-releasing hormone (GnRH) B Hypersecretion of pituitary LH and FSH as the result of increased GnRH C Excess secretion of testicular activin by Seoli cells D Failure of the hypothalamus to respond to testosterone 💡 Explanation A major causal factor in some cases of hypogonadism is ✓ Correct Answer: A. Reduced secretion of gonadotropin-releasing hormone (GnRH)