A lady when exposed to Cold, Extremities turn to blue. Which of the following antibody is associated with it?
Correct Answer: Anti SCL-70
Description: The above scenario is described as Raynaud's phenomenon, which is seen in Scleroderma. Raynaud's phenomenon Fibrosis of skin around digital blood vessels On Cold exposure due to abnormal vasoconstriction Tip of fingers turns white. Antinuclear antibody (ANA) is the most sensitive antibody in scleroderma and is the preferred screening test. Anti-centromere antibody is most specific for CREST syndrome. Anti-topoisomerase I (Scl-70)is most specific fordiffuse systemic sclerosis/diffused Scleroderma.
Category:
Anatomy
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now