Pharmacology A known case of COPD is on treatment with theophylline. Which of the following side effect will be commonly seen due to inhibition of PDE4? A Headache B Diuresis C Cardiac arrhythmias D Epileptic seizures 💡 Explanation A known case of COPD is on treatment with theophylline. Which of the following side effect will be commonly seen due to inhibition of PDE4? ✓ Correct Answer: A. Headache