A highly ionized drug
Correct Answer: Is excreted mainly by kidney
Description: Ionized molecules cannot cross the biological membranes .therfore they are less likely to be absorbed . Entry of the molecules through blood brain barrier and blood placental barrier is also restricted .these drugs cannot be reabsorbed in the nephron,thus are excreted by the kidney . Refer kDT 7/e p29
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Anatomy
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