A female patient presented with a firm mass of 2 x 2 cms in the upper outer quadrant of the breast. She gives a family history of ovarian carcinoma. The investigation that needs to be done to assess for mutation is :
Correct Answer: BRCA-2
Description: Ans. is 'b' BRCA 2 "In women with hereditary breast - ovarian cancer, two susceptibility loci have been identified:BRCA -1 - located on chromosome 17 andBRCA - 2 - located on chromosome 13" - Harrison, 15/e, p620
Category:
Pathology
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