A farmer presented in OPD clinic with sweating, lacrimation, pin-point pupils. Possible poisoning with:
Correct Answer: Organophosphate poisoning
Description: Ans. (b) Organophosphate poisoningRef Katzung Pharamacology 10th ed. Ch 7* In organophosphate poisoning, the organophosphate cholinesterase inhibitors are well absorbed from the skin, lung, gut, and conjunctiva--thereby making them dangerous to humans and highly effective as insecticides.* These organophosphates irreversibly block acetylcholine esterase enzyme, thereby increasing the acetylcholine level.* The patient therefore will present with cholinergic symptoms: (Mn: SLUDGE)* Salivation, Lacrimation, increased urination, Diarreha, GI distress, Emesis* DOC for this poisoning: ATROPINEAlso Know* OXIMES (Pralidoximes, Di-Acetyl monoxime) are known as AchE enzyme reactivators. These are used only in organophosphate poisoning.Pin-point pupil is seen in poisoning with: (Mn: POMP)* Pontine hemorrhage, Organophosphate, Morphine and Phenol poisoning
Category:
Pharmacology
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now