Pharmacology A drug that binds to a receptor at a site distinct from the active site and reduces the affinity of the receptor for the endogenous ligand is a: A Competitive antagonist B Paial antagonist C Inverse agonist D Allosteric antagonist 💡 Explanation A drug that binds to a receptor at a site distinct from the active site and reduces the affinity of the receptor for the endogenous ligand is a: ✓ Correct Answer: D. Allosteric antagonist