Pharmacology A direct-acting cholinomimetic that is lipid soluble and has been used in the treatment of glaucoma is: A Acetylcholine B Physostigmine C Pilocarpine D Neostigmine 💡 Explanation A direct-acting cholinomimetic that is lipid soluble and has been used in the treatment of glaucoma is: ✓ Correct Answer: C. Pilocarpine