Pathology A dens in dente is usually caused by: A An abnormal proliferation of pulp tissue B Denticle formation within the pulp tissue C A deep invagination of the enamel organ during formation D A supernumerary tooth bud enclaved within a normal tooth. 💡 Explanation A dens in dente is usually caused by: ✓ Correct Answer: C. A deep invagination of the enamel organ during formation