A codon consists of:
So the core concept here is the structure of a codon. The options aren't provided, but the correct answer is likely to be that a codon consists of three nucleotides. Let me think about why that's the case. In DNA, the genetic code is read in triplets, called codons, which are transcribed into mRNA as three nucleotides. Each triplet corresponds to an amino acid or a stop signal. For example, the codon AUG codes for methionine and also serves as the start codon.
Now, the possible wrong options might suggest two nucleotides (like a dinucleotide) or four, but those are incorrect. Other options might confuse codons with anticodons found in tRNA, which also have three nucleotides but pair with the mRNA codons. Another possible wrong answer could be something like three amino acids, which is not correct because codons are part of the mRNA that codes for amino acids, not composed of them.
The clinical pearl here is remembering that the genetic code is triplet, so any question about codons should immediately make you think of three nucleotides. This is fundamental in understanding how genes are translated into proteins and is a key point in exams like NEET PG or USMLE.
**Core Concept**
A codon is a sequence of **three adjacent nucleotides** in mRNA that specifies a particular amino acid or a termination signal during protein synthesis. This triplet code is universal, ensuring accurate translation of genetic information into proteins.
**Why the Correct Answer is Right**
The genetic code is read in triplets, with each codon consisting of **three nucleotides** (e.g., AUG for methionine). During translation, ribosomes read mRNA in these 3-nucleotide segments, matching them to tRNA anticodons to append the correct amino acid to the growing polypeptide chain. This triplet system allows 64 possible codons (4Β³), sufficient to encode 20 amino acids plus start/stop signals.
**Why Each Wrong Option is Incorrect**
**Option A:** If suggesting 2 nucleotides, this is incorrect because a dinucleotide cannot encode all 20 amino acids or start/stop signals.
**Option C:** If suggesting 4 nucleotides, this violates the established triplet code, which is the basis of all known life forms.
**Option D:** If suggesting amino acids, this is wrong because codons are nucleotide sequences, not amino acids themselves.
**Clinical Pearl / High-Yield Fact**
**"Triplet code, 64 codons, 20 amino acids"** is a must-remember. The redundancy (multiple codons for one amino acid) and universal nature (shared across species) of the genetic code are frequently tested in exams. Always associate codons with **mRNA nucleotides**, not tRNA anticodons or amino acid sequences.
**Correct Answer: C. Three nucleotides**