Patients who are found to have Barrett's oesophagus may be submitted to regular surveillance endoscopy with multiple biopsies in the hope of finding dysplasia or in situ cancer rather.Annual endoscopy has been widely practised, but two-year intervals are probably adequate, provided no dysplasia has been detected.High-dose PPI treatment or an antireflux operation, these endoscopic ablation methods can result in a neosquamous lining. But there is no evidence yet that any of these methods are reliable in eliminating cancer risk.Bailey and Love 26th edition pg: 1002