A child with a constellation of findings including fever, disabling ahritis, rash, and blindness is MOST likely suffering form
Correct Answer: Juvenile rheumatoid ahritis
Description: JUVENILE RHUEMATOID AHRITIS : A child with a constellation of findings including fever, disabling ahritis, rash, and blindness is most likely suffering from juvenile rheumatoid ahritis (JRA). JRA is characterized by a chronic synol inflammation of unknown origin; it most commonly affects the knees, but can also manifest in wrists, ankles, and the atlantoaxial joint in the neck. In general, JRA is more common in girls than boys, but this varies with the type of JRA, which can be divided into the following variant subsets: Still disease (20%), polyaicular (40%), and pauciaicular (40%). Still, the disease most closely resembles an infectious disease, with spiking fever, a centripetal rash, generalized lymphadenopathy, hepatosplenomegaly, transient ahralgias and ahritis, and effusions (pericardial and plural). The polyaicular variant is associated with destructive ahritis, paicularly if the patient tests positive for the rheumatoid factor. The pauciaicular variant features polyahritis and inflammation of the anterior uveal tract 10%-50%), which predisposes the patient to visual loss and blindness. In most cases of JRA, with the Exception of the polyaicular variant, the rheumatoid factor is negative. Anemia and leukocytosis are noted in acute attacks. Aspirin is the major anti-inflammatory agent that is used for treatment. Regarding the other choices in the question: rheumatic fever features polyahritis, but it is not destructive Lyme disease displays many of these findings, but blindness is not a key feature Henoch-Schoenlein vasculitis has palpable purpura, non-disabling ahritis, but is not associated with blindness dermatomyositis does not usually involve the joints Ref: Maheshwari 9TH ED pg 286.
Category:
Orthopaedics
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now