Microbiology A child was admitted to the hospital with H. influenza meningitis. Cefotaxime is preferred over ampicillin because: A Cefotaxime is more bioavailable B Cefotaxime is more active against altered penicillin binding protein C Drug of choice is trimethoprim sulfamethoxazole but cannot be given D Cefotaxime is more active against beta-lactamase 💡 Explanation A child was admitted to the hospital with H. influenza meningitis. Cefotaxime is preferred over ampicillin because: ✓ Correct Answer: D. Cefotaxime is more active against beta-lactamase