A child present with recurrent sinusitis and recurrent chest infections. Chest X–ray reveals dextrocardia and situs invertus. The diagnosis is –
Correct Answer: Kartagener's syndrome
Description: Kartagener's syndrome is a subgroup of primary ciliary dyskinesia.
Primary ciliary dyskinesia:
It is an autosomal recessive syndrome.
It is characterized by poorly functioning cilia. There is absence or shortening of Dynein arms that are responsible for the coordinated bending of cilia.
Approximately half of the patients with primary ciliary dyskinesia have kartagener's syndrome.
Category:
Pediatrics
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