A child diagnosed with acute lymphocytic leukemia (ALL) is under chemotherapy. Which of the following is a BAD prognostic sign of ALL?
Correct Answer: Age above 10 years
Description: Children aged 1-9 years whose diagnostic WBC count is less than 50,000/microliter, standard risk ALL, have an event-free survival (EFS) in the 90% range, while children 10 years of age or older have an EFS of approximately 88%. Other high-risk factors for ALL: Non-T-cell disease Adverse cytogenetics Extramedullary disease Failure to achieve remission within 30 days of treatment Ref: Graham D.K., Quinones R.R., Keating A.K., Maloney K., Foreman N.K., Giller R.H., Greffe B.S. (2012). Chapter 31. Neoplastic Disease. In W.W. Hay, Jr., M.J. Levin, R.R. Deterding, J.J. Ross, J.M. Sondheimer (Eds), CURRENT Diagnosis & Treatment: Pediatrics, 21e.
Category:
Pediatrics
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now