Pathology A characteristic histologic feature of class IV lupus nephritis is A "Holly leaf" mesangial deposits B "Spike and dome" appearance of the basement membrane C "Wire-loop" appearance of the glomerular capillaries D "Tram-track" splitting of the basement membrane 💡 Explanation A characteristic histologic feature of class IV lupus nephritis is ✓ Correct Answer: C. "Wire-loop" appearance of the glomerular capillaries