A cervical Pap smear repo stating that “koilocytic atypia is present” indicates the:-

Correct Answer: Cytologic effect of human papillomavirus
Description: HPV infection of squamous cells Produces wrinkled nuclei surrounded by a clear halo. This is called koilocytosis. Whether it is indicative of a low or a high grade lesion in the cervix requires tissue documentation. This is usually obtained with a colposcopic biopsy.
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