A blood donor is not considered for safe transfusion, if he has –

Correct Answer: HBsAg +ve and IgM anti HBc +ve
Description: Ans. is 'c' i.e., HBs Ag + ye and IgM anti HBc +ve . HBs Ag(+)ve and IgM anti HBc (+)ve indicates acute HBV infection, which is a contraindication of blood tranfusion. About other options Option a . Anti HBs Ag antibody may be (+)ve either after immunization or after recovery from HBV infection. In both the conditions, blood can be transfused. Option b . HBc Ag can not be (+)ve as it does not appear in blood. Option c . When Anti HBe is (+)ve blood can be transfused if other markers of infection are also negative eg: HBsAg, HBV DNA, IgM anti HBC.
Category: Microbiology
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