A 75-year-old woman with rheumatoid arthritis (RA) takes aspirin for symptom control. She usually adjusts the dose of her own medications depending on how she is feeling.For the above patient with a toxic ingestion or exposure, select the most likely clinical effect.
Correct Answer: vertigo, hyperventilation, tinnitus, and deafness
Description: Salicylates are associated with vertigo, hyperventilation, tinnitus, and deafness. Excretion of salicylates is renal, and in the presence of normal renal function, about 50% will be excreted in 24 hours. Severe toxicity can cause severe acid-base abnormalities. It can be difficult to diagnose when the toxicity is secondary to a therapeutic regimen.
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