A 70 year old male patient dies with severe dementia. Autopsy demonstrates marked atrophy of the frontal and temporal lobes, with relative sparing of the rest of the brain. Which of the following microscopic features would be most useful in establishing the diagnosis?
A 70 year old male patient dies with severe dementia. Autopsy demonstrates marked atrophy of the frontal and temporal lobes, with relative sparing of the rest of the brain. Which of the following microscopic features would be most useful in establishing the diagnosis?
💡 Explanation
A 70 year old male patient dies with severe dementia. Autopsy demonstrates marked atrophy of the frontal and temporal lobes, with relative sparing of the rest of the brain. Which of the following microscopic features would be most useful in establishing the diagnosis?
✓ Correct Answer: B. Intracytoplasmic spherules composed of paired helical filaments
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