A 6-month child presented with diarrhea and vomiting for three days. Which of the following enterotoxin is most likely responsible for the condition?
Correct Answer: NSP4
Description: Ans. A. NSP4Rotavirus nonstractural protein 4 (NSP4) is known to function as an intracellalar receptor at the endoplssmic reticalam (ER) critical to virul morphogenesis and is the first characterized virul enterotoxin.The associntion of NSP4 snd cuveolin-I contributes to NSP4 intrqcellular trfficking from the ER to the cell surfuce and speculate that exogenously added NSP4 stimulutes sigaaling molecules located in caveola microdomains.
Category:
Microbiology
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