Answer: c) Captopril.* In 0.1% to 0.5% of patients, ACE inhibitors induce a rapid swelling in the nose, throat, mouth, glottis, larynx, lips, and/or tongue.* This untoward effect, called angioedema, apparently is not dose-related, and if it occurs, it does so within the first week of therapy, usually within the first few hours after the initial dose.* Airway obstruction and respiratory distress may lead to death.* It may involve accumulation of bradykinin, induction of tissue-specific autoantibodies, or inhibition of complement 1-esterase inhibitor.* Once ACE inhibitors are stopped, angioedema disappears within hours.* Although it is rare, angioedema of the intestine (visceral angioedema) also has been reported in association with ACE inhibitors.* Visceral angioedema is characterized by emesis, watery diarrhea, and abdominal pain.* Most cases of visceral angioedema occur in the absence of oropharyngeal edema.