Medical MCQ - A 55-year-old male was diagnosed with pulmonary tuberculosis and staed on standard 4 drug regimen. After 1.5 months, the patient developed peripheral neuropathy. Deficiency of a paicular vitamin is responsible for peripheral neuropathy. This vitamin does not paicipate in which one of the following processes?

A 55-year-old male was diagnosed with pulmonary tuberculosis and staed on standard 4 drug regimen. After 1.5 months, the patient developed peripheral neuropathy. Deficiency of a paicular vitamin is responsible for peripheral neuropathy. This vitamin does not paicipate in which one of the following processes?

Niacin production

Heme synthesis

Glycogen synthesis

Transamination

Question Category:

Unknown

Correct Answer:

Glycogen synthesis

Description:

Peripheral neuropathy is due to isoniazid induced pyridoxine deficiency. Niacin production: Kinureninanse is a PLP dependent enzyme Heme synthesis: ALA synthase is a PLP dependent enzyme Transamination: aminotransferases are PLP dependent enzymes Glycogenolysis: glycogen phosphorylase is a PLP dependent enzyme However, glycogen synthase enzyme does not depend on PLP as a co enzyme.

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