A 55-year-old male presented with complaints of apathy, disinhibition, and compulsive behaviour, loss of empathy, overeating, easy forgetfulness and amnesia. There is also a family history of dementia. MRI of the brain was ordered. A brain biopsy was also taken and HPE examination was done. What is the most likely Diagnosis?
Correct Answer: Frontotemporal dementia
Description: The history of early personality changes followed by memory loss along with Pick cell (ballooned cell with dissolution of chromatin suggestive of pick body) is suggestive of Picks disease. MRI shows anterior cingulate and frontoinsular atrophy, spreading to orbital and dorsolateral prefrontal coex. OPTION A- Alzheimer's disease would have early memory loss, later symptoms of personality changes. Option B - Vascular dementia would have focal neurological deficit due to stroke and a step ladder progression. Option D - Lewy body dementia would show fluctuating amnesia with visual hallucination with spontaneous Parkinsonism.
Category:
Unknown
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now